KOH mount as an aid in the management of infectious keratitis at secondary eye care centre
| Autor: | Savitri Sharma, Rohit C Khanna, Varsha M Rathi, Prashant Garg, Monica Thakur |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Microbiological Techniques 0301 basic medicine medicine.medical_specialty Antifungal Agents Adolescent genetic structures Cefazolin Infectious Keratitis Eye care Keratitis Cornea Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Natamycin Pregnancy Ophthalmology parasitic diseases medicine Humans In patient Child Aged Retrospective Studies Cross Infection business.industry Fungi Disease Management Middle Aged medicine.disease eye diseases Sensory Systems 030104 developmental biology medicine.anatomical_structure Corneal scrapings 030221 ophthalmology & optometry Female business Eye Infections Fungal medicine.drug |
| Zdroj: | British Journal of Ophthalmology. 101:1447-1450 |
| ISSN: | 1468-2079 0007-1161 |
| DOI: | 10.1136/bjophthalmol-2017-310241 |
| Popis: | Aims To report the clinical outcome of infectious keratitis managed after doing 10% KOH mount of corneal smears and reporting done by an ophthalmologist in the secondary eye care centre in South India. Methods 103 consecutive cases of microbial keratitis were studied. Inclusion criteria were presence of corneal infiltrate on slit lamp biomicroscopy. An ophthalmologist carried out microbiological evaluation of 10% KOH mount of corneal scrapings. No cultures were done at secondary centres. Antifungal therapy with 5% Natamycin was initiated when 10% KOH mount was positive for fungal filaments. Else, the patients were started on combined topical ciprofloxacin (0.3%) and fortified cefazolin (5%). Results 41/103 (39.8%) smears were positive for fungus and 62 (60.2%) were negative. 89 out of 103 patients (86.40%) healed with scarring at an average of 2.95±1.58 weeks. Healing was noted in 39/41 (95.12%) of patients at an average of 3.06±1.19 weeks in patients with KOH smear positive keratitis. 80.64% (50/62) healed with scarring at an average period of 2.86±1.86 weeks in KOH mount negative keratitis. Conclusions Initial smear examination of KOH mount by an ophthalmologist helped in diagnosis of infectious keratitis caused by fungi and its management and 95.12% of KOH positive patients healed with scarring. Reading of KOH mount by an ophthalmologist helped in initiation of specific therapy with improved clinical outcome. |
| Databáze: | OpenAIRE |
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