Expression of transmembrane 4 superfamily member, CD9, is related to improved progression-free survival in patients with diffuse non-Hodgkin's lymphoma
| Autor: | J C Yau, K S Formenti, B F Burns, L K Dabbagh, A R Shaw, R W Coupland |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Cancer Research Adolescent Biopsy Biology Disease-Free Survival Tetraspanin 29 Actuarial Analysis Antigens CD medicine Humans Progression-free survival Aged Neoplasm Staging Aged 80 and over Membrane Glycoproteins Oncogene Lymphoma Non-Hodgkin Cancer General Medicine Cell cycle Middle Aged medicine.disease Prognosis Molecular medicine Hodgkin Disease Immunohistochemistry Transmembrane protein Lymphoma Survival Rate Oncology embryonic structures Cancer research Female |
| Zdroj: | Oncology reports. 5(6) |
| ISSN: | 1021-335X |
| Popis: | Decreased expression of the transmembrane 4 superfamily member, CD9, is associated with poor prognosis in patients with breast or non-small cell lung cancer. The expression of CD9 in lymphoma was examined in this study. Fifty-one sections with diffuse lymphomas were examined. Thirty-seven had low expression and 14 high expression of CD9. At 5 years the progression-free survival rates were 83.3+/-10.8% and 32.8+/-9.2% (p=0.018), and the actual survival were 83.3+/-10.8% and 56.8+/-8.9% (p=0.256) for those with high and low CD9 expression respectively. Decreased expression of CD9 appears to be a prognostic factor for poor survival in patients with diffuse lymphomas. |
| Databáze: | OpenAIRE |
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