Discoid Lupus Erythematosus Involving the Eyelids
| Autor: | Paul B. Donzis, Denise M. Buntin, Michael S. Insler, Leonard E. Gately |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Discoid lupus erythematosus Periorbital Edema Fluorescent Antibody Technique Lesion Lupus Erythematosus Discoid Forearm medicine Edema Humans Lymphocytes Skin Dermoepidermal junction business.industry Hydroxychloroquine medicine.disease Dermatology Ophthalmology medicine.anatomical_structure Immunoglobulin M Immunoglobulin G Eyelid Diseases Female Eyelid medicine.symptom business medicine.drug |
| Zdroj: | American Journal of Ophthalmology. 98:32-36 |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/0002-9394(84)90185-5 |
| Popis: | Of two patients with discoid lupus erythematosus with eyelid involvement, one, a 42-year-old man, had a one-year history of persistent periorbital edema and a violaceous discoloration as the sole manifestation. Although treatment with corticosteroids and antihistamines failed to produce improvement, the patient had an excellent clinical response to systemic hydroxychloroquine therapy. Histologic examination with immunofluorescent staining demonstrated deposition of immunoglobulins at the dermoepidermal junction. The second patient, a 37-year-old woman, had a hyperpigmented lesion on her forearm as the initial symptom but later developed similar lesions elsewhere, including her lower eyelid. Treatment with hydroxychloroquine again produced an excellent response. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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