A Cautionary Tale About a Bridesmaid's DRESS

Autor: Madeleine W. Schrier, Brian Alverson
Rok vydání: 2016
Předmět:
Zdroj: Hospital pediatrics. 6(8)
ISSN: 2154-1663
Popis: A previously healthy 18-year-old girl with no significant medical history presented to her pediatrician in the summer with a sore throat and fatigue. Results of a rapid Streptococcus (strep) screening test and a mononucleosis spot test were both negative, and she was prescribed a 10-day course of amoxicillin for the pharyngitis. One week later, the patient returned with a diffuse rash consisting of small red macules and papules on her trunk, arms, and face, consistent with amoxicillin use in the setting of infectious mononucleosis (IM). Laboratory tests for Epstein-Barr virus (EBV) immunoglobulin G and immunoglobulin M returned positive, the amoxicillin was discontinued, and a 6-day course of prednisone was prescribed in an effort to help manage her symptoms. Ten days later, after completing the course of steroids, the patient visited a dermatologist for painful pustules that had developed on her legs and buttocks. Concerned about infection with methicillin-resistant Staphylococcus aureus (MRSA), her dermatologist cultured the pustules and prescribed topical mupirocin 2% cream and 100 mg twice daily of minocycline for the folliculitis while awaiting culture results (which later returned as methicillin-sensitive S aureus ). One week after the patient started the minocycline, she noticed a pruritic rash on her legs that spread to her trunk, arms, and face over the next few days. She subsequently developed a fever of 104°F with chills and fatigue; she visited the emergency department, where she was prescribed triamcinolone cream, hydroxyzine, and cetirizine and was discharged. The rash continued to worsen, and the patient developed swelling of her face, lips, neck, hands, and feet. …
Databáze: OpenAIRE