Influence of exogenous gangliosides (G(M1), G(D1a), G(Mix)) on a Ca(2+)-activated Mg(2+)-dependent ATPase in cellular and subcellular brain fractions of the djungarian dwarf hamster (Phodopus sungorus)

Autor: Hinrich Rahmann, K Slenzka, Ramona Appel
Rok vydání: 1989
Předmět:
Zdroj: Neurochemistry international. 17(4)
ISSN: 0197-0186
Popis: The influence of 150 nM exogenously-added gangliosides (G(M1), G(D1a), G(Mix)) on a Ca(2+)-activated, Mg(2+)-dependent ATPase was investigated in cellular and subcellular fractions (P1-fraction, synaptosomal fraction, synaptic membranes) from whole brain, cortex, cerebellum and brain stem of the djungarian dwarf hamster (Phodopus sungorus). Gangliosides are effective at this concentration in stimulating the enzyme activity in all fractions from whole brain. Inhomogenous results (stimulation, inhibition and no effects), however, were obtained in the different individual brain regions.
Databáze: OpenAIRE