Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children
| Autor: | Rachel L. Maguire, Cathrine Hoyo, Scott H. Kollins, Bernard F. Fuemmeler, Yaou Sheng, Carmen E. Sanchez, Nancy Zucker, Susan K. Murphy |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Health Toxicology and Mutagenesis lcsh:Medicine Article Body Mass Index Executive Function 03 medical and health sciences 0302 clinical medicine Risk Factors 030225 pediatrics North Carolina medicine Humans Attention deficit hyperactivity disorder ADHD 030212 general & internal medicine Early childhood Child 2. Zero hunger child development Pregnancy Working memory business.industry Confounding lcsh:R Public Health Environmental and Occupational Health medicine.disease Child development maternal obesity Attention Deficit Disorder with Hyperactivity Child Preschool Prenatal Exposure Delayed Effects gestational weight gain Regression Analysis Female pregnancy medicine.symptom business Body mass index Weight gain Follow-Up Studies Clinical psychology |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 16, Iss 4, p 667 (2019) International Journal of Environmental Research and Public Health Volume 16 Issue 4 |
| ISSN: | 1660-4601 |
| Popis: | This study examines pre-pregnancy Body Mass Index (BMI) and gestational weight gain (GWG) in relation to early childhood Attention Deficit Hyperactivity Disorder (ADHD) symptoms and related executive self-regulation behaviors. The analyses sample (n = 331) included a subsample of participants from a birth cohort recruited from prenatal clinics and hospital facilities from April 2005 to June 2011 in Durham, North Carolina. Pre-pregnancy BMI was calculated from weight at the last menstrual period and height was extracted from medical records. Gestational weight gain was calculated from pre-pregnancy weight and weight measured at the time of delivery. ADHD symptoms and executive self-regulation behaviors were assessed by maternal report (mean age = 3 years). Multivariable regression methods with inverse probability weighting (IPW) were used to evaluate associations accounting for sample selection bias and confounding. Pre-pregnancy BMI at levels &ge 35 was positively associated with higher ADHD symptoms and worse executive self-regulation behaviors (inhibitory control and attention). Compared to adequate GWG, less than adequate GWG was related to more ADHD hyperactive-impulsive symptoms, whereas greater than adequate GWG was related to more problematic behaviors related to working memory and planning. The findings support a link between maternal weight and child neurodevelopment. Continued research that help identify biological mechanisms are needed. |
| Databáze: | OpenAIRE |
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