Elastography in the Differential Diagnosis of Thyroid Nodules
| Autor: | Tuncay Delibasi, Nujen Colak Bozkurt, Erman Cakal, Askin Gungunes, Mustafa Sahin, Mustafa Ozbek, Evrim Çakır Özkaya, Ilknur Ozturk Unsal, Esra Tutal Akkaymak |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Male
Thyroid nodules medicine.medical_specialty Goiter Population Malignancy Sensitivity and Specificity Diagnosis Differential medicine Humans Outpatient clinic Radiology Nuclear Medicine and imaging Prospective Studies Thyroid Nodule education Aged education.field_of_study Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Thyroid Reproducibility of Results Nodule (medicine) Middle Aged medicine.disease medicine.anatomical_structure Area Under Curve Elasticity Imaging Techniques Female Radiology Elastography medicine.symptom business |
| Zdroj: | Ultrasonic Imaging. 37:251-257 |
| ISSN: | 1096-0910 0161-7346 |
| Popis: | Despite the publication of a recent meta-analysis of elastography in thyroid nodules, further work is necessary on this issue in different populations. In this study, we aimed to evaluate the clinical value of elastography on nodular goiters in mild iodine-deficient regions without excluding patients according to nodule characteristics. This prospective study was conducted between April 2010 and December 2011 in Yıldırım Beyazıt Dıskapı Research Hospital Endocrinology outpatient clinic. Five hundred twenty-eight nodular goiter patients who underwent thyroid fine-needle aspiration biopsy were included in our study. Elastography scores and indexes were measured with real-time ultrasound elastography (Hitachi® EUB 7000 HV machine with 13 MHz linear transducer). There were 471 females and 57 males and their ages ranged from 45 years to 78 years. A total of 601 nodules were evaluated in these patients. The area under the curve (AUC) for the elasto score was 0.91 ( p < 0.0001) and AUC for the strain index (SI) was 0.96 ( p < 0.0001). We suggest that the SI reflects malignancy better than the elasto score. We conclude that elastography scores greater than 3 have 76% sensitivity and 96% specificity for diagnosing malignancy. For SI, we conclude that 3.75 (83% sensitivity and 95% specificity) is the cutoff point. Elasto score and SI measurements of thyroid nodules in our population are efficient and increase the diagnostic performance of the sonography. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|