Allenylphosphine oxides as simple scaffolds for phosphinoylindoles and phosphinoylisocoumarins
Autor: | K. C. Kumara Swamy, G. Gangadhararao, Ramesh Kotikalapudi, M. Nagarjuna Reddy |
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Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Allenylphosphine
Isocoumarins Organic Chemistry organophosphorus indoles Full Research Paper lcsh:QD241-441 Solvent chemistry.chemical_compound Chemistry lcsh:Organic chemistry chemistry allenes Propargyl propargyl alcohols Trifluoroacetic acid Organic chemistry lcsh:Q phosphinoyl-heterocycles lcsh:Science Single crystal isocoumarins |
Zdroj: | Beilstein Journal of Organic Chemistry Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 996-1005 (2014) |
ISSN: | 1860-5397 |
Popis: | A range of phosphinoylindoles was prepared in one-pot from functionalized propargyl alcohols and a suitable P(III) precursor via a base-mediated reaction. The reaction proceeds via the intermediacy of allenylphosphine oxides. Similarly, phosphinoylisocoumarins were prepared from allenylphosphine oxides in a trifluoroacetic acid-mediated reaction; the latter also acts as a solvent. Interestingly, in the presence of wet trifluoroacetic acid, in addition to phosphinoylisocoumarins, phosphorus-free isocoumarins were also obtained. Key products were characterized by single crystal X-ray crystallography. |
Databáze: | OpenAIRE |
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