The timing of stereotactic radiosurgery for medically refractory trigeminal neuralgia: the evidence from diffusion tractography images
| Autor: | Wen Yuh Chung, Chih Chun Wu, Hsiu Mei Wu, Shin Tai Chong, Wan-Yuo Guo, Ching-Jen Chen, Jason P. Sheehan, Chung Jung Lin, Cheng-Chia Lee, Huai-Che Yang, David Hung-Chi Pan, Ching Po Lin, Sheng-Che Hung |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Time Factors medicine.medical_treatment Radiosurgery 030218 nuclear medicine & medical imaging White matter 03 medical and health sciences 0302 clinical medicine Trigeminal neuralgia Fractional anisotropy medicine Humans Pain Management Trigeminal Nerve Aged Retrospective Studies Aged 80 and over Trigeminal nerve business.industry Cranial nerves Hypoesthesia Middle Aged Trigeminal Neuralgia medicine.disease Diffusion Tensor Imaging medicine.anatomical_structure Female Surgery Neurology (clinical) medicine.symptom business Nuclear medicine 030217 neurology & neurosurgery Diffusion MRI |
| Zdroj: | Acta Neurochirurgica. 160:977-986 |
| ISSN: | 0942-0940 0001-6268 |
| DOI: | 10.1007/s00701-017-3449-9 |
| Popis: | Diffusion tensor imaging (DTI) is a novel MRI technique that enables noninvasive evaluation of microstructural alterations in white matter of brain. Initially, DTI was used in intra- or inter-hemispheric association bundles. Recent technical advances are overcoming the challenges of imaging small white matter bundles, such as the cranial nerves. In this study, we use DTI to shed more light on the microstructure changes in long-standing trigeminal neuralgia. We also utilize DTI to study the effect of early stereotactic radiosurgery (SRS) on the microstructures of the trigeminal nerve and to predict the effectiveness of early SRS in the treatment of medically refractory trigeminal neuralgia (TN). To analyze the presentation of trigeminal nerve, the DTI was reconstructed in 21 cases pre- and post-SRS. DTI parameters recorded include fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), axial diffusivity (AD), linear anisotropy coefficient (Cl), planar anisotropy coefficient (Cp), and spherical anisotropy coefficient (Cs). Comparisons between ipsilateral (symptomatic) and contralateral (asymptomatic) trigeminal nerves and symptom durations of |
| Databáze: | OpenAIRE |
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