Diagnosis of Acute Rejection With Cardiac Ultrasound
| Autor: | Christoph H. Spes, Hans-Ulrich Stempfle, Karl Theisen, Andres R. Tammen, C. E. Angermann, Bruno Reichart |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Graft Rejection
Heart transplantation Transplantation medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Ultrasound Reproducibility of Results Immunosuppression Gold standard (test) Doppler echocardiography Sensitivity and Specificity Echocardiography Doppler Cardiac Ultrasound Echocardiography Acute Disease Heart Transplantation Humans Medicine Surgery Radiology Stage (cooking) business |
| Zdroj: | Transplantation Proceedings. 30:893-894 |
| ISSN: | 0041-1345 |
| Popis: | ACUTE rejection (AR) following heart transplantation (HTX) is characterized histologically by patchy or diffuse cellular infiltrates, interstitial oedema, and, if AR is more severe, by myocyte necrosis and hemorrhage. Main criterion for the usefulness of any diagnostic tool is its capability to rapidly and reliably detect AR at the latest stage when intensified immunosuppression is required. For many years, histology from endomyocardial biopsies (EMB) has remained the gold standard; no other method has been shown to consistently fulfill this requirement. All attempts to diagnose AR noninvasively by ultrasound aim at identification of its morphologic and functional consequences. Several approaches have been employed: Conventional M-mode and two-dimensional echocardiography (2D-E), pulsed Doppler (D) E and E-based tissue analysis, using either videodensitometry or 2D integrated backscatter (IB) measurements based on unprocessed radiofrequency (RF) data. More recently, Doppler Tissue Imaging (DTI) has been proposed as a diagnostic tool. This article reviews the published literature on AR diagnosis based on cardiac ultrasound and discusses practical usefulness and limitations of the various techniques. |
| Databáze: | OpenAIRE |
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