Some observations on the fine structure of human granulosa cell tumors
| Autor: | Genton Cy |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
endocrine system Hormonal activity Histology Prominent nucleoli Mitochondrion Endoplasmic Reticulum Agranular endoplasmic reticulum Pathology and Forensic Medicine Humans Molecular Biology Aged Granulosa Cell Tumor Cell Nucleus Ovarian Neoplasms urogenital system Chemistry Cell Biology General Medicine Middle Aged Granulosa cell tumors Mitochondria Cell biology Microscopy Electron Granular Endoplasmic Reticulum Ultrastructure Female Anatomy Lysosomes Cell Nucleolus |
| Zdroj: | Virchows Archiv A Pathological Anatomy and Histology. 387:353-369 |
| ISSN: | 1432-2307 0340-1227 |
| DOI: | 10.1007/bf00454838 |
| Popis: | The ultrastructural features of three granulosa cell tumors are presented. The neoplastic non-luteinized granulosa cells are characterized at sub-microscopical level by severely indented nuclei with prominent nucleoli, sparse to moderately developed predominantly granular endoplasmic reticulum, scanty lipids and lysosomes, small mitochondria with lamellar cristae and abundant intracytoplasmic filamentous material. The luteinized cells display a strongly developed tubular agranular endoplasmic reticulum and mitochondria with tubular cristae. These findings are compared with those of previous reports and discussed in relation to the well-known hormonal activity of these tumors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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