Risk factors for osteonecrosis severity among Egyptian systemic lupus erythematosus patients: Magnetic resonance imaging (MRI) staging

Autor: Amal Ibrahim Ahmed Othman, Takwa B. Younes, Sherin Mohamed Hosny Hamza, Nermine Samy
Rok vydání: 2019
Předmět:
Zdroj: Egyptian Rheumatologist, Vol 41, Iss 4, Pp 295-301 (2019)
ISSN: 1110-1164
DOI: 10.1016/j.ejr.2018.12.007
Popis: Aim of the work: To determine the risk factors of bilateral and severe (advanced) osteonecrosis femoral head (ONFH) as assessed by magnetic resonance imaging (MRI) staging in Egyptian SLE patients. Patients and methods: Sixty SLE patients were studied and subdivided into two groups according to the presence or absence of symptomatic osteonecrosis. Full medical history, musculoskeletal examination, laboratory and serologic tests were done to all patients. SLE disease activity index (SLEDAI), systemic lupus international collaboration clinics damage index (SLICC/DI), health assessment questionairre (HAQ) disability index and the visual analogue scale (VAS-pain) were assessed. 30 patients with symptomatic ONFH were identified and staged by MRI according to Ficat and Arlet classification. Dual energy x-ray absorptiometry (DEXA) scan was performed. Results: The mean age at-onset of patients with ONFH was significantly lower than those without (20.7 ± 5.9 vs 30.4 ± 7.9 years; p
Databáze: OpenAIRE