Cryptococcal Lung Infections
| Autor: | Christopher H. Mody, Shaunna M. Huston, Kate Skolnik |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pulmonary and Respiratory Medicine Antifungal Agents 030106 microbiology Cryptococcus Disease Flucytosine 03 medical and health sciences Amphotericin B medicine Humans Lung Respiratory Tract Infections Cryptococcus gattii Cryptococcus neoformans biology business.industry Cryptococcosis bacterial infections and mycoses biology.organism_classification medicine.disease Immunology business Fluconazole medicine.drug |
| Zdroj: | Clinics in Chest Medicine. 38:451-464 |
| ISSN: | 0272-5231 |
| Popis: | Cryptococcus is among the most common invasive fungal pathogens globally and is one of the leading causes of acquired immunodeficiency virus-related deaths. Cryptococcus neoformans and Cryptococcus gattii are the most clinically relevant species and account for most cryptococcal disease. Pulmonary manifestations can range from mild symptoms to life-threatening infection. Treatment is tailored based on the severity of pulmonary infection, the presence of disseminated or central nervous system disease, and patient immune status. Amphotericin B and flucytosine followed by fluconazole remain the standard agents for the treatment of severe cryptococcal infection. |
| Databáze: | OpenAIRE |
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