An evaluation of 6 dentifrice formulations for supragingival anticalculus and antiplaque activity
| Autor: | Richard C. Graves, Paul W. Stewart, Lewis Cancro, Gregory Payonk, Judith A. Disney |
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| Rok vydání: | 1989 |
| Předmět: |
Dental Plaque
Dentistry Positive control Placebo Placebo group Citric Acid Phosphates Double blind Fluorides Double-Blind Method Aluminum Oxide medicine Dentifrice Humans Dental Calculus Citrates Dentifrices Clinical Trials as Topic business.industry Calculus (dental) Silicon Dioxide medicine.disease Lower incisor Zinc stomatognathic diseases Evaluation Studies as Topic Plaque inhibition Regression Analysis Periodontics business |
| Zdroj: | Journal of Clinical Periodontology. 16:525-528 |
| ISSN: | 1600-051X 0303-6979 |
| DOI: | 10.1111/j.1600-051x.1989.tb02330.x |
| Popis: | A 4 week, double blind clinical trial was conducted to assess the antiplaque/anticalculus activity of test dentifrices containing varying levels of zinc citrate. Subjects were divided into 6 groups, 4 experimental, 1 positive control and a placebo group. All subjects only brushed at home using the placebo control during study weeks 1 and 3. Plaque and calculus were collected at the end of study weeks 2 and 4 on mylar strips worn on lower incisor teeth. Dentifrice efficacy was assessed by comparing group dry and ash weight decrements. While there were no significant differences between the test and control groups, there was a demonstrable trend toward greater inhibition with higher zinc citrate levels, especially among subjects with high levels of plaque and calculus at baseline. |
| Databáze: | OpenAIRE |
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