Berberine Ameliorates Lipopolysaccharide-Induced Cognitive Impairment Through SIRT1/NRF2/NF-κB Signaling Pathway in C57BL/6J Mice

Autor:	Nan Chen, Xin-Chen Wang, Ling-Ling Fan, Yu-Huang Zhu, Qi Wang, Yun-Bo Chen
Rok vydání:	2022
Předmět:	Lipopolysaccharides Aging Berberine NF-E2-Related Factor 2 Anti-Inflammatory Agents NF-kappa B Isoquinolines Antioxidants Mice Inbred C57BL Mice Sirtuin 1 Animals Cognitive Dysfunction Geriatrics and Gerontology Heme Oxygenase-1 Drugs Chinese Herbal Signal Transduction
Zdroj:	Rejuvenation research. 25(5)
ISSN:	1557-8577
Popis:	The inflammatory response is the stress reactions to infection or injury so as to help the body return to normal as soon as possible. In central nervous system, the overactivated immune system causes irreversible damage to neurons and synapses, which results in cognitive impairment. Berberine, an isoquinoline alkaloid extracted from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c1299aceb251e488e1513e85348b92 https://pubmed.ncbi.nlm.nih.gov/36029207 Zobrazit plný text záznamu