Quality of surgical care can impact survival in patients with bladder cancer after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium

Autor: Mani Menon, Paul May, Justen Kozlowski, Amir Khan, Lee Richstone, Joan Palou Redorta, Mevlana Derya Balbay, Alexandre Mottrie, Prokar Dasgupta, Matthias Saar, Michael Stöckle, John Benkowski, Franco Gaboardi, Abolfazl Hosseini, Mohammad Shamim Khan, Koon Ho Rha, John F. Kelly, Francis Schanne, Peter Wiklund, Ayesha Durrani, Wei Shen Tan, Basel Ahmad, Thomas J. Maatman, Bertram Yuh, Ashok K. Hemal, Jihad H. Kaouk, Ahmed A. Hussein, Youssef Ahmed, Saira Khan, Khurshid A. Guru, Vassilis Poulakis, James O. Peabody, Carl Wijburg, Giovannalberto Pini, Andrew A. Wagner, Abdullah Erdem Canda
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: African Journal of Urology, Vol 26, Iss 1, Pp 1-8 (2020)
ISSN: 1961-9987
1110-5704
DOI: 10.1186/s12301-020-00031-y
Popis: Background Although pathological factors remain the main determinate of survival for patients with bladder cancer, quality of surgical care is crucial for satisfactory outcomes. Using a validated quality score, we investigated the impact of surgical factors on the overall survival (OS), recurrence-free survival (RFS) and disease-specific survival (DSS) in patients with locally advanced and organ-confined disease (OCD). Retrospective review of IRCC database includes 2460 patients from 29 institutions across 11 countries. The final cohort included 1343 patients who underwent RARCs between 2005 and 2016. Patients with locally advanced disease (LAD) (> pT2 and/or N +) were compared with OCD (≤ pT2/N0). Validated Quality Cystectomy Score (QCS) based on four sets of quality metrics was used to compare surgical performance. Kaplan–Meier method was used to compute RFS, CSS and OS rates. Multivariable stepwise logistic regression was used to evaluate variables associated with RFS, DSS and OS. Results 48% had LAD. When compared to patients with OCD, they received neobladders less frequently (17% vs. 28%, p p = 0.05). Postoperatively, more patients in the LAD group received adjuvant chemotherapy (24% vs. 4%, p p p Conclusion Quality of surgical care can affect disease control and OS in patients with bladder cancer treated with robot-assisted radical cystectomy.
Databáze: OpenAIRE
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