Usefulness of coronary flow reserve over regional wall motion when added to dual-imaging dipyridamole echocardiography
| Autor: | M. Richieri, Fausto Rigo, Antonio Raviele, V. Cutaia, Eugenio Picano, Patrizia Della Valentina, Emilio Pasanisi, C. Zanella, Francesco Di Pede |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Chest Pain Diastole Coronary Disease Chest pain Coronary Angiography Coronary artery disease Coronary circulation Predictive Value of Tests Internal medicine Coronary Circulation medicine Stress Echocardiography Humans Ultrasonography business.industry Coronary flow reserve Dipyridamole Middle Aged medicine.disease medicine.anatomical_structure Cardiology Linear Models Female medicine.symptom Cardiology and Cardiovascular Medicine business Artery medicine.drug |
| Zdroj: | The American journal of cardiology. 91(3) |
| ISSN: | 0002-9149 |
| Popis: | Vasodilator stress echocardiography allows semi-simultaneous imaging of left anterior descending (LAD) coronary flow and regional wall function. To assess the relative (and additive?) value of regional flow and function for noninvasive identification of angiographically assessed LAD disease in patients with chest pain syndrome, we studied 230 consecutive in-hospital patients (134 men, aged 63.5 +/- 11 years) with chest pain syndrome and normal regional and global left ventricular function. All patients underwent stress echocardiography with dipyridamole (up to 0.84 mg/kg over 10 minutes), including wall motion analysis by 2-dimensional echocardiography and coronary flow reserve (CFR) evaluation of the LAD artery by Doppler, with or without contrast injection. A new regional wall motion abnormality in >or=2 contiguous segments was required for 2-dimensional echocardiographic positivity. CFR was evaluated as the ratio of dipyridamole to peak diastolic coronary blood flow velocity at rest. All patients underwent coronary angiography within 60 days; a quantitatively assessed diameter reduction >50% of the LAD artery was considered significant. Of the 230 patients, 70 had LAD disease. A regional wall motion abnormality in LAD territory was present in 52 patients, and reduced CFR ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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