Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424

Autor:	Vatcharin Rukachaisirikul, Wipapan Pongcharoen, Masahiko Isaka, Sanisa Lapanun, Sirinya Chantaruk
Rok vydání:	2006
Předmět:	Stereochemistry Antitubercular Agents Pharmaceutical Science Microbial Sensitivity Tests Analytical Chemistry Mycobacterium tuberculosis chemistry.chemical_compound Ascomycota Drug Discovery Lachnum Phenols Nuclear Magnetic Resonance Biomolecular Antibacterial agent Pharmacology chemistry.chemical_classification biology Molecular Structure Organic Chemistry Biological activity biology.organism_classification Thailand Complementary and alternative medicine chemistry Chromones Chromone Molecular Medicine Lactone Bacteria
Zdroj:	Journal of natural products. 69(6)
ISSN:	0163-3864
Popis:	Five new chromones, named lachnones A-E (1-5), were isolated from the filamentous fungus Lachnum sp. BCC 2424 along with known (2E,6S)-2,6-dimethyl-2,7-octadiene-1,6-diol. Their structures were elucidated by spectroscopic methods. Lachnones B (2) and D (4) mildly inhibited the growth of Mycobacterium tuberculosis, both with MIC values of 200 microg/mL.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ac55516a938c9b0c6b0fa9c6e96ab3 https://pubmed.ncbi.nlm.nih.gov/16792425 Zobrazit plný text záznamu