Dissociative symptoms are associated with reduced neuropsychological performance in patients with recurrent depression and a history of trauma exposure

Autor: Margaret C. McKinnon, Paul A. Frewen, Ruth A. Lanius, Carolina Oremus, Melissa Parlar
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: European Journal of Psychotraumatology, Vol 7, Iss 0, Pp 1-9 (2016)
European Journal of Psychotraumatology
ISSN: 2000-8066
Popis: Background : Although preliminary work suggests that dissociative symptoms may impact neuropsychological performance in trauma-exposed populations, the relation between dissociation and cognitive performance has not been explored in patients with depression. Objective : The present study examined dissociative symptoms in relation to neuropsychological performance in participants with a primary diagnosis of recurrent major depressive disorder (MDD) and a history of trauma exposure. Method : Twenty-three participants with MDD and 20 healthy controls who did not differ in age, sex, education, or IQ were assessed. In addition to a standardized neuropsychological battery assessing frontotemporally mediated cognitive processes, participants completed clinical measures assessing dissociative symptoms, illness severity, and past history of trauma exposure. Results : Among participants with MDD, greater severity of derealization was associated with reduced performance on measures of delayed visuospatial recall and recognition on a task of verbal memory recognition. In addition, more severe depersonalization was associated with slower processing speed and a response style lending itself toward better performance in a less active environment. Conclusions : These findings point toward dissociative symptoms as a transdiagnostic factor associated with neuropsychological dysfunction in patients with depression and a history of trauma. Limitations and recommendations for future research are discussed. Keywords: cognition; depression; dissociation; transdiagnostic; traumatic stress (Published: 25 February 2016) Responsible Editor: Ulrike Schmidt, Max Planck Institute of Psychiatry, Germany. For the abstract or full text in other languages, please see Supplementary files in the column to the right (under ‘Article Tools’) Citation: European Journal of Psychotraumatology 2016, 7 : 29061 - http://dx.doi.org/10.3402/ejpt.v7.29061 Citation: European Journal of Psychotraumatology 2016, 7 : 29061 - http://dx.doi.org/10.3402/ejpt.v7.29061 Responsible Editor: Ulrike Schmidt, Max Planck Institute of Psychiatry, Germany. Copyright: © 2016 Melissa Parlar et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License , allowing third parties to copy and redistribute the material in any medium or format, and to remix, transform, and build upon the material, for any purpose, even commercially, under the condition that appropriate credit is given, that a link to the license is provided, and that you indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. Received: 5 July 2015; Accepted: 1 December 2015; Published: 25 February 2016 Competing interests and funding: There is no conflict of interest in the present study for any of the authors. * Correspondence to: Margaret C. McKinnon, Mood Disorders Research Unit, St. Joseph’s Healthcare, 100 West 5th Street, Box 585, Hamilton, ON, Canada, Email: mmckinno@stjosham.on.ca For the abstract or full text in other languages, please see Supplementary files under ‘Article Tools’
Databáze: OpenAIRE
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