Cutaneous leishmaniasis caused by Leishmania tropica in Algeria
| Autor: | Frédérique de Monbrison, I. Mihoubi, Nadia Hafirassou, Stéphane Picot |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Leishmania tropica Leishmaniasis Cutaneous Rural Health Polymerase Chain Reaction Treatment failure Diagnosis Differential Cutaneous leishmaniasis Epidemiology medicine Animals Humans Species identification Protozoal disease biology Transmission (medicine) business.industry Urban Health Public Health Environmental and Occupational Health Kinetoplastida General Medicine DNA Protozoan biology.organism_classification medicine.disease Dermatology Infectious Diseases Algeria Parasitology business |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 102:1157-1159 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/j.trstmh.2008.06.013 |
| Popis: | Cutaneous leishmaniasis is endemic in Algeria, but clinical and parasitological data from this area are scarce. In order to document the transmission of this disease in a peri-urban setting, cutaneous lesions from patients living in Constantine City and surrounding areas were spotted on filter paper for diagnosis and species identification using real-time PCR. Surprisingly, Leishmania tropica was detected in 6/69 patients, and confirmation was obtained by sequencing. This observation suggests a modification of the epidemiology of cutaneous leishmaniasis in Algeria and should alert physicians and policy-makers to the risk of antimony treatment failure with this species. |
| Databáze: | OpenAIRE |
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