Occupational asthma caused by roasted coffee: immunologic evidence that roasted coffee contains the same antigens as green coffee, but at a lower concentration
| Autor: | Catherine Lemière, Marjorie McCants, Jean-Luc Malo, S.B. Lehrer |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Allergy medicine.medical_specialty Hot Temperature Immunology Occupational disease Dose-Response Relationship Immunologic medicine.disease_cause Coffee Allergen Vasomotor Rhinitis medicine Immunology and Allergy Humans Antigens Asthma business.industry Incidence (epidemiology) medicine.disease Dermatology Surgery Occupational Diseases Etiology business Occupational asthma |
| Zdroj: | The Journal of allergy and clinical immunology. 98(2) |
| ISSN: | 0091-6749 |
| Popis: | controlled studies, in which the numbers of patients with a positive history ranged from 24 to 37. Although reactions occurred to both non-[3-1actam antimicrobials and nonantimicrobial drugs, the frequency of these reactions was not greater in group A or B, compared with group C, which suggests that the existence of a history of penicillin allergy causing a change in prescribing habits was not a factor and that there was no significant difference in reporting patterns. Only one patient in the vasomotor rhinitis group gave a history of penicillin allergy, and this patient had no history of a reaction to non-[3-1actam drugs. Because patients with a history of penicillin allergy in this study have an incidence of reactions to non[3-1actam drugs that is equal to that found in the vasomotor rhinitis group, they do have multiple drug reactions, because they reacted to both [3-1actarn and non-[~-lactam drugs. But the risk of reacting to non-[3-1actams is not increased in either patients with a positive history of penicillin allergy or those with skin test-proven penicillin allergy, when compared with the control rhinitis group. So although this survey is also subject to the deficiencies of retrospective evaluation and limited by the preponderance of female subjects and sample size, it does suggest, in contrast to previous studies, that the development of penicillin allergy and non-[3-1actam allergy are not associated, but occur independently. |
| Databáze: | OpenAIRE |
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