Massive Systemic Amyloidosis Associated with Light-Chain Deposition Disease
| Autor: | D. Ganeval, B. Hurault De Ligny, M. Leporrier, Xavier Troussard, B. Gallet, Jean-Philippe Ryckelynck, Mandard Jc |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Pathology
medicine.medical_specialty Amyloid Thyroid Gland Spleen Kidney Light chain deposition disease medicine Humans Multiple myeloma Aged business.industry Myocardium Amyloidosis Thyroid medicine.disease medicine.anatomical_structure Liver Kidney Failure Chronic Female Immunoglobulin Light Chains Bone marrow Multiple Myeloma business Pancreas |
| Zdroj: | Nephron. 52:139-143 |
| ISSN: | 2235-3186 1660-8151 |
| DOI: | 10.1159/000185616 |
| Popis: | A 72-year-old woman presented with rapidly progressive renal failure and multiple myeloma. The patient died 6 months later of severe hepatic insufficiency. The light-microscopic, immunological and ultrastructural findings showed widespread kappa-light-chain deposits including the kidneys, liver, spleen, heart, lungs, tongue, ovary, pancreas and bone marrow associated with massive AL amyloid deposits in the same organs and in the thyroid gland. The concurrent presence of two different deposits is very unusual and the possible mechanisms for such an association are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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