Age estimation in dental pulp DNA based on human telomere shortening
| Autor: | Akiko Tsuji, Masamichi Ohishi, Noriaki Ikeda, Tomoya Takasaki |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Aging
business.industry Forensic Sciences Dentistry DNA Telomere Biology Pathology and Forensic Medicine Restriction fragment Time of death Andrology stomatognathic diseases chemistry.chemical_compound Japan stomatognathic system Dna genetics chemistry Age estimation biology.protein Humans Forensic odontology business Dental Pulp |
| Zdroj: | International Journal of Legal Medicine. 117:232-234 |
| ISSN: | 1437-1596 0937-9827 |
| DOI: | 10.1007/s00414-003-0376-5 |
| Popis: | Age estimation based on evidence found in teeth has received considerable attention within the field of forensic science. We determined the terminal restriction fragment (TRF) length, as telomere length, to estimate age. Using dental pulp DNA we found the average TRF length showed a tendency to shortening with aging. Our findings show that telomere shortening, based on dental pulp DNA is a new and useful approach to estimate age of the subject at the time of death. |
| Databáze: | OpenAIRE |
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