The effects of dietary protein on the somatotropic axis: a comparison of soy, gelatin, alpha-lactalbumin and milk

Autor: Margriet A. B. Veldhorst, A. J. A. H. van Vught, R.J.M. Brummer, Margriet S. Westerterp-Plantenga, Arie G. Nieuwenhuizen
Přispěvatelé: Humane Biologie, RS: NUTRIM - R1 - Metabolic Syndrome
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: European Journal of Clinical Nutrition, 64(5), 441-446. Nature Publishing Group
ISSN: 0954-3007
DOI: 10.1038/ejcn.2010.21
Popis: Background/Objectives:Growth hormone (GH) is an important regulator of growth and body composition. It has been shown that GH release can be promoted by administration of various amino acids (AAs), such as arginine and lysine, that are present in soy protein. We previously showed that oral ingestion of soy protein stimulates the GH release, it is not known however to which extent other proteins stimulate the GH secretion.Subjects/Methods:Ingestion of soy protein (soy), gelatin protein (gelatin), alpha-lactalbumin protein (alpha-lactalbumin) and milk protein (milk) were compared on their GH-stimulating capacity. After oral ingestion of protein (0.6 g protein per kg bodyweight), blood was sampled every 20 min for 5 h to analyze GH, AA, insulin and glucose concentrations. The study was performed in eight healthy women (aged 19-26 years; body mass index 19-26 kg/m(2)) in a randomized, single blind, placebo-controlled crossover design.Results:GH responses were more increased after ingestion of gelatine (8.2+/-1.1 mug/l) compared with ingestion of soy, alpha-lactalbumin and milk (5.0+/-0.8, 4.5+/-0.6 and 6.4+/-1.0 mug/l, respectively) (P
Databáze: OpenAIRE