Pigmented neurofibroma: Report of two cases and literature review
| Autor: | Tetsuji Yamamoto, Chiho Ohbayashi, Mayumi Inaba, Keisuke Hanioka, Rieko Minami |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Skin Neoplasms CD34 Antigens CD34 Pigmented dermatofibrosarcoma protuberans Cytoplasmic Granules Pathology and Forensic Medicine Diagnosis Differential Immunoenzyme Techniques Abdominal wall Antigens Neoplasm Dermatofibrosarcoma protuberans medicine Humans Neurofibromatosis Pigmented Neurofibroma Melanins Neurofibroma Pigmentation business.industry Dermatofibrosarcoma S100 Proteins General Medicine Middle Aged medicine.disease Dermatology Neoplasm Proteins medicine.anatomical_structure Female business Melanoma-Specific Antigens |
| Zdroj: | Pathology International. 51:565-569 |
| ISSN: | 1440-1827 1320-5463 |
| DOI: | 10.1046/j.1440-1827.2001.01235.x |
| Popis: | Two cases of pigmented neurofibroma of the skin are reported. In case 1, the tumor was removed from the back of a 55-year-old man with no associated neurofibromatosis. In case 2, the tumor was removed from the abdominal wall of a 21-year-old woman with neurofibromatosis. Both tumors consisted of benign, short spindle cells and multiple foci of scattered melanin-laden cells. In case 1, the spindle cells were arranged in a storiform pattern, resembling features of dermatofibrosarcoma protuberans. Immunohistochemically, the spindle cells of both cases were demonstrated to be positive for S-100 protein and CD34. The melanin-laden cells stained positively for HMB-45. This report describes an additional two cases of pigmented neurofibroma that conform to the new diagnostic criteria for this disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|