Intravenous immunoglobulin therapy in severe lupus myocarditis: good outcome in three patients
| Autor: | D Micheloud, M Caparrros, D P D'Cruz, M Calderón |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Myocarditis Systemic lupus erythematosus Heart disease biology business.industry Immunology Neutropenia medicine.disease Gastroenterology General Biochemistry Genetics and Molecular Biology Surgery Intravenous Immunoglobulin Therapy medicine.anatomical_structure Rheumatology Internal medicine medicine biology.protein Immunology and Allergy Letters Antibody skin and connective tissue diseases Low Complement business Respiratory tract |
| Popis: | Myocarditis occurs in 8–78% of necropsy studies of patients with systemic lupus erythematosus (SLE)1,2 but is rare in clinical practice. We describe three patients with severe lupus myocarditis, who improved dramatically after intravenous immunoglobulin (IVIg) therapy. Table 1 gives details of the cases studied. View this table: Table 1 Characteristics of the patients studied A 37-year-old woman (patient 3) was diagnosed with lupus, confirmed by strongly positive anti-DNA, low complement, and positive anti-RNP and anti-Sm antibodies. She developed breathlessness and a restrictive lung function pattern and received mycophenolate. She was admitted with a respiratory tract infection, neutropenia (1.6×10 … |
| Databáze: | OpenAIRE |
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