RETROSPENIAL CORTICAL DEACTIVATION DURING PAINFUL STIMULATION OF FIBROMYALGIC PATIENTS

Autor:	Mats Fredrikson, Håkan Fischer, Gustav Wik, Björn Bragée, Marianne Kristianson, Basil Finer
Rok vydání:	2006
Předmět:	Adult Pain Threshold Fibromyalgia Pain Hemodynamics Painful Stimulation Functional Laterality Positron emission tomographic Retrosplenial cortex Parietal Lobe Neural Pathways medicine Humans Acute pain Brain Mapping business.industry General Neuroscience General Medicine Middle Aged medicine.disease Frontal Lobe Cerebral blood flow Hyperalgesia Cerebrovascular Circulation Positron-Emission Tomography Anesthesia Female medicine.symptom Arousal business
Zdroj:	International Journal of Neuroscience. 116:1-8
ISSN:	1543-5245 0020-7454
DOI:	10.1080/00207450690962208
Popis:	To study fibromyalgic pain this article contrasts positron emission tomographic measures of regional cerebral blood flow (rCBF) during externally induced acute pain and rest in eight fibromyalgia syndrome patients. An expected pattern of frontal and parietal cortical activation during acute pain as compared to rest was observed. However, reduced rCBF was additionally found in the retrosplenial cortex during acute pain as compared to rest. This may reflect that externally induced pain inhibits fibromyalgic pain and syndrome-related evaluative processes located in the retrosplenial cortex, and that fibromyalgic pain results from exaggerated attention to sub-noxious pain signaling, that is, secondary hyperalgesia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028248a80bc33d90afbaf0e90f7a2df1 https://doi.org/10.1080/00207450690962208 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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