Measures of clinical efficacy. Cost-effectiveness calculations in the diagnosis and treatment of hypertensive renovascular disease
| Autor: | Burrows Ba, Barbara J. McNeil, Stephen Adelstein, Varady Pd |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Hypertension Renal Cost effectiveness Population urologic and male genital diseases Renovascular hypertension Intravenous Pyelogram Medicine Humans False Positive Reactions cardiovascular diseases Clinical efficacy Hypertensive renovascular disease education False Negative Reactions health care economics and organizations education.field_of_study business.industry Bayes Theorem Urography General Medicine medicine.disease female genital diseases and pregnancy complications United States Iodohippuran Costs and Cost Analysis Iodohippuric Acid Radiology Renovascular disease business Radioisotope Renography |
| Zdroj: | The New England journal of medicine. 293(5) |
| ISSN: | 0028-4793 |
| Popis: | The sensitivity and specificity of the hypertensive intravenous pyelogram and the iodohippuran renogram have been determined for the diagnosis of renovascular disease, and cost-effectiveness calculations have been made for the diagnosis and surgical treatment of patients with renovascular hypertension. When the intravenous pyelogram alone is used to screen representative hypertensive population, 78 per cent of patients with renovascular disease are located, but at the same time an equal number of patients without renovascular diasease have abnormal pyelograms. The renogram, on the other hand, is associated with varying true-positive and false-positive ratios. These data can be plotted in the form of a receiver-operating-characteristic curve. The cost of finding a patient with renovascular disease is about $2,000, and that of a surgical cure is about $20,000. The number of deaths for 100 surgical cures is approximately 15. The dollar cost of screening and treating the total American renovascular hypertensive population is of the order of 10 to 13 billion dollars. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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