Extraprostatic extension of gleason 6 prostate cancer: single center experience
| Autor: | Onur Ceylan, Rabia Demirtas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry 030232 urology & nephrology Urology Specialties of internal medicine Single Center medicine.disease prostate cancer Diseases of the genitourinary system. Urology 03 medical and health sciences Prostate cancer 0302 clinical medicine RC581-951 030220 oncology & carcinogenesis extraprostatic extension medicine gleason score Medicine RC870-923 Extraprostatic extension business |
| Zdroj: | Yeni Üroloji Dergisi, Vol 16, Iss 2, Pp 165-170 (2021) |
| ISSN: | 2687-1955 1305-2489 |
| Popis: | Objective: For Gleason Score (GS) 3+3:6 prostate cancer (PC) cases, recent guidelines recommend clinical follow-up instead of radical treatment due to complications. One of the most important disadvantages of clinical follow-up is that low-grade PC may include local aggressive behavior. Hence, our aim here was to investigate the incidence of extraprostatic extension (EPE), a local aggressive behavior, in GS6 PC cases. Material and Methods: We examined 119 materials diagnosed with prostatic adenocarcinoma (GS 3+3:6) with no tertiary pattern and that were sent to our department as radical prostatectomy materials between January 2010 – May 2019. We investigated how many of the materials had EPE. Results: We observed EPE in 16 (13.45%) of our cases. 5 of the cases had vesicula seminalis invasion (pT3b) and 11 had EPE and/or bladder neck invasion (pT3a) without vesicula seminalis invasion. Conclusion: Among our patients diagnosed with GS-6 PC, we observed EPE (pT3) in 13.45% and vesicula seminalis invasion (pT3b) in 4.2%, which suggests that the possibility of EPE is not uncommon in GS-6 PC. Based on these findings, we argue that patients with GS-6 PC under clinical follow-up should be followed more carefully for EPE. Keywords: prostate cancer; gleason score; extraprostatic extension |
| Databáze: | OpenAIRE |
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