Autor: |
Alvin Man Lung Chan, Angela Min Hwei Ng, Mohd Heikal Mohd Yunus, Ruszymah Bt Hj Idrus, Jia Xian Law, Muhammad Dain Yazid, Kok-Yong Chin, Sharen Aini Shamsuddin, Mohd Rafizul Mohd Yusof, Rabiatul Adawiyah Razali, Mohd Asyraf Mat Afandi, Muhammad Najib Fathi Hassan, See Nguan Ng, Benson Koh, Yogeswaran Lokanathan |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Regenerative therapy. 19 |
ISSN: |
2352-3204 |
Popis: |
Intravenous (IV) infusion of mesenchymal stem cells (MSCs) from nascent tissues like Wharton's Jelly of the umbilical cord is reported to offer therapeutic effects against chronic diseases. However, toxicological data essential for the clinical application of these cells are limited. Thus, this study aimed to determine the safety of IV infusion of Wharton's Jelly derived MSCs (WJ-MSCs) in rats. Fifteen male Sprague-Dawley rats were randomised into the control or treatment group. Each group received an equal volume of saline or WJ-MSC (10 × 10 |
Databáze: |
OpenAIRE |
Externí odkaz: |
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