National multi-centre study found a low prevalence of severely impaired lung function in children and adolescents
| Autor: | Ana Lukić, Frederik Buchvald, Lone Agertoft, Sune Rubak, Marianne Skov, Michael Perch, Kim G. Nielsen |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
lung disease
Cystic Fibrosis Adolescent diagnosis prevalence spirometry lung function General Medicine respiratory system respiratory tract diseases Cross-Sectional Studies Spirometry Cystic Fibrosis/complications Forced Expiratory Volume Pediatrics Perinatology and Child Health Prevalence Humans Child Lung |
| Zdroj: | Lukić, A, Buchvald, F, Agertoft, L, Rubak, S, Skov, M, Perch, M & Nielsen, K G 2022, ' National multi-centre study found a low prevalence of severely impaired lung function in children and adolescents ', Acta Paediatrica, International Journal of Paediatrics, vol. 111, no. 5, pp. 1044-1051 . https://doi.org/10.1111/apa.16262 |
| Popis: | Aim: As no data to our knowledge exist, the aim of the study was to describe the national prevalence and characteristics of Danish children and adolescents with severely impaired lung function. Methods: We performed a descriptive, cross-sectional Danish multi-centre study. Children and adolescents between 6 and 18 years old demonstrating severely impaired lung function from 2015 to 2018, defined by forced expiratory volume in 1 second (FEV1) 1 was 46.1% (10.1%) of predicted, and z-score was −4.5 (0.8). The most frequent diagnosis was cystic fibrosis (20.4%), followed by asthma (19.5%) and bronchiolitis obliterans (16.8%), while almost 25% had different elements of airway malformations or non-pulmonary conditions. Two adolescents with cystic fibrosis underwent lung transplantation. Conclusion: The estimated prevalence of severely impaired lung function in Danish children and adolescents was low, and extremely, few children underwent lung transplantation. The most frequent diagnosis was cystic fibrosis, while almost 25% had different elements of airway malformations or non-pulmonary conditions, which may require clinical attention. |
| Databáze: | OpenAIRE |
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