Microfluidic preparation of monodisperse polymeric microspheres coated with silica nanoparticles
| Autor: | Kyoung Ku Kang, Chang-Soo Lee, Byungjin Lee, Si Hyung Jin, Dong-Yeong Kim, Seong-Geun Jeong |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Multidisciplinary
Fabrication Materials science lcsh:R Dispersity Microfluidics lcsh:Medicine 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Methacrylate 01 natural sciences Article 0104 chemical sciences Micrometre Ammonium hydroxide chemistry.chemical_compound Chemical engineering X-ray photoelectron spectroscopy chemistry Particle lcsh:Q lcsh:Science 0210 nano-technology |
| Zdroj: | Scientific Reports Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018) |
| ISSN: | 2045-2322 |
| Popis: | The synthesis of organic-inorganic hybrid particles with highly controlled particle sizes in the micrometer range is a major challenge in many areas of research. Conventional methods are limited for nanometer-scale fabrication because of the difficulty in controlling the size. In this study, we present a microfluidic method for the preparation of organic-inorganic hybrid microparticles with poly (1,10-decanediol dimethacrylate-co-trimethoxysillyl propyl methacrylate) (P (DDMA-co-TPM)) as the core and silica nanoparticles as the shell. In this approach, the droplet-based microfluidic method combined with in situ photopolymerization produces highly monodisperse organic microparticles of P (DDMA-co-TPM) in a simple manner, and the silica nanoparticles gradually grow on the surface of the microparticles prepared via hydrolysis and condensation of tetraethoxysilane (TEOS) in a basic ammonium hydroxide medium without additional surface treatment. This approach leads to a reduction in the number of processes and allows drastically improved size uniformity compared to conventional methods. The morphology, composition, and structure of the hybrid microparticles are analyzed by SEM, TEM, FT-IR, EDS, and XPS, respectively. The results indicate the inorganic shell of the hybrid particles consists of SiO2 nanoparticles of approximately 60 nm. Finally, we experimentally describe the formation mechanism of a silica-coating layer on the organic surface of polymeric core particles. |
| Databáze: | OpenAIRE |
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