Autor: |
Francisco Javier López-Longo, Javier Martín, José A. Miranda-Filloy, Ricardo Blanco, Alfonso Corrales, Trinitario Pina, Mercedes García-Bermúdez, Miguel A. González-Gay, Begoña Ubilla, Fernanda Genre, Javier Llorca, Carmen Gómez-Vaquero, Santos Castañeda, Alejandro Balsa, Raquel López-Mejías, Isidoro González-Álvaro, Carlos González-Juanatey, Benjamín Fernández-Gutiérrez, Patricia Carreira, Dora Pascual-Salcedo, Luis Rodriguez-Rodriguez |
Přispěvatelé: |
Universidad de Cantabria, Universitat de Barcelona |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
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Zdroj: |
PLoS ONE, Vol 9, Iss 9, p e106823 (2014) PLoS One. 2014 Sep 3;9(9):e106823 UCrea Repositorio Abierto de la Universidad de Cantabria Universidad de Cantabria (UC) Digital.CSIC. Repositorio Institucional del CSIC instname Recercat. Dipósit de la Recerca de Catalunya Dipòsit Digital de la UB Universidad de Barcelona PLoS ONE |
ISSN: |
1932-6203 |
Popis: |
© 2014 Genre et al. Introduction: Rheumatoid arthritis is an inflammatory disease with high incidence of cardiovascular disease due to accelerated atherosclerosis. Osteoprotegerin (OPG) has been associated with increased risk of atherosclerotic disease in the general population. Several polymorphisms in the OPG gene with functional effects on cardiovascular disease in nonrheumatic individuals have been described. Therefore, we aimed to analyze the effect of three of these functional OPG polymorphisms on the risk of cardiovascular disease in a large and well-characterized cohort of Spanish patients with rheumatoid arthritis. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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