An ELISA Procedure for Detecting Human Anti-Endotoxin Antibodies in Serum
| Autor: | John G. Brock-Utne, Gaffin Sl, B. J. Vorster, J D Conradie, Nasima Badsha |
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| Rok vydání: | 1982 |
| Předmět: |
030213 general clinical medicine
biology business.industry Clinical Biochemistry Enzyme-Linked Immunosorbent Assay 030209 endocrinology & metabolism General Medicine Anti-endotoxin antibodies Antibodies Bacterial Endotoxins 03 medical and health sciences 0302 clinical medicine Immunology biology.protein Humans Mass Screening Blood units Medicine Antibody Elisa method business Blood bank |
| Zdroj: | Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 19:191-194 |
| ISSN: | 1758-1001 0004-5632 |
| DOI: | 10.1177/000456328201900313 |
| Popis: | We report an ELISA method suitable for the large-scale screening of blood bank stores to identify those blood units containing high concentrations of antiendotoxin antibodies. In Natal, 8·3% of total units collected had antiendotoxin antibodies at concentrations greater than 40 μg/ml, values that may be therapeutically useful. We found that one technician could screen enough samples per year to produce 800 litres of such high-titre plasma. |
| Databáze: | OpenAIRE |
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