Effects of antioxidant system on coronary artery lesions in patients with abnormal glucose metabolism

Autor: Lin-Hui Shen, Wei Liang, Ya-Jie Zhao, Hui Yang
Rok vydání: 2016
Předmět:
Blood Glucose
Male
China
Aging
medicine.medical_specialty
Statistics as Topic
Glutathione reductase
030204 cardiovascular system & hematology
Carbohydrate metabolism
Coronary Angiography
medicine.disease_cause
Severity of Illness Index
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Risk Factors
Internal medicine
Diabetes mellitus
Humans
Medicine
Aged
chemistry.chemical_classification
Glutathione Peroxidase
Superoxide Dismutase
business.industry
Glutathione peroxidase
Coronary Stenosis
Glutathione
Middle Aged
Catalase
medicine.disease
Coronary Vessels
Oxidative Stress
Glutathione Reductase
medicine.anatomical_structure
Endocrinology
chemistry
Hyperglycemia
030220 oncology & carcinogenesis
Female
Blood sugar regulation
Geriatrics and Gerontology
business
Oxidative stress
Artery
Zdroj: Aging Clinical and Experimental Research. 29:141-146
ISSN: 1720-8319
DOI: 10.1007/s40520-016-0564-z
Popis: To evaluate the effects of catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) system on the range and severity of coronary artery lesions in patients with abnormal glucose metabolism. This study included 766 patients with abnormal glucose metabolism. Levels of fasting blood lipids, blood glucose, CAT, SOD, GSH, glutathione reductase (GR), and glutathione peroxidase (GSH-Px) were measured in all the patients. Coronarography was performed, and the degree of the lesions in each coronary artery was quantitatively analyzed using the Gensini scoring system. In patients with impaired glucose regulation and diabetes, the number of coronary artery branches with stenosis and the Gensini scores were inversely correlated with the plasma levels of CAT, SOD, GSH, GH, and GSH-Px (P
Databáze: OpenAIRE
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