National Institute of Infectious Diseases
| Autor: | Allan ole Kwallah, Shingo Inoue, Kouichi Morita, Anne Wangari Thairu-Muigai, Nancy Kuttoh, Matilu Mwau |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Microbiology (medical) Adolescent Yellow fever vaccine Biology Antibodies Viral Virus Viral hemorrhagic fever Young Adult Seroepidemiologic Studies Yellow Fever medicine Humans Seroprevalence Child Yellow Fever Vaccine Yellow fever Infant Outbreak General Medicine Middle Aged medicine.disease Kenya Virology Vaccination Infectious Diseases Child Preschool Immunoglobulin G Female Health Facilities Yellow fever virus medicine.drug |
| Zdroj: | Japanese Journal of Infectious Diseases. 68:230-234 |
| ISSN: | 1884-2836 1344-6304 |
| DOI: | 10.7883/yoken.jjid.2014.288 |
| Popis: | Yellow fever (YF), which is caused by a mosquito-borne virus, is an important viral hemorrhagic fever endemic in equatorial Africa and South America. Yellow fever virus (YFV) is the prototype of the family Flaviviridae and genus Flavivirus. The aim of this study was to determine the seroprevalence of YFV in selected health facilities in Western Kenya during the period 2010?2012. A total of 469 serum samples from febrile patients were tested for YFV antibodies using in-house IgM-capture ELISA, in-house indirect IgG ELISA, and 50z focus reduction neutralization test (FRNT50). The present study did not identify any IgM ELISA-positive cases, indicating absence of recent YFV infection in the area. Twenty-eight samples (6z) tested positive for YFV IgG, because of either YFV vaccination or past exposure to various flaviviruses including YFV. Five cases were confirmed by FRNT50; of these, 4 were either vaccination or natural infection during the YF outbreak in 1992?1993 or another period and 1 case was confirmed as a West Nile virus infection. Domestication and routine performance of arboviral differential diagnosis will help to address the phenomenon of pyrexia of unknown origin, contribute to arboviral research in developing countries, and enhance regular surveillance. Japanese Journal of Infectious Diseases, 68(3), pp.230-234; 2015 |
| Databáze: | OpenAIRE |
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