A novel system for automated propofol sedation: hybrid sedation system (HSS)
| Autor: | Shantale Cyr, Mohamad Wehbe, Cédrick Zaouter, Francesco Giunta, Thomas M. Hemmerling, Riccardo Taddei, Erik Arbeid |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Sedation Conscious Sedation Health Informatics Anesthesia General Critical Care and Intensive Care Medicine Propofol sedation 03 medical and health sciences Automation 0302 clinical medicine 030202 anesthesiology Anesthesiology Anesthesia Closed-Circuit medicine Chi-square test Humans Prospective Studies Closed-loop Prospective cohort study Perioperative Period Propofol Aged Automated sedation business.industry 030208 emergency & critical care medicine Anesthesiology and Pain Medicine Perioperative Equipment Design Middle Aged Decision Support Systems Clinical Surgery Treatment Outcome Bispectral index Anesthesia Anesthesia Intravenous Female medicine.symptom business Anesthetics Intravenous medicine.drug |
| Popis: | Closed-loop systems for propofol have been demonstrated to be safe and reliable for general anesthesia. However, no study has been conducted using a closed-loop system specifically designed for sedation in patients under spinal anesthesia. We developed an automatic anesthesia sedation system that allows for closed-loop delivery of propofol for sedation integrating a decision support system, called the hybrid sedation system (HSS). The objective of this study is to compare this system with standard practice. One hundred fifty patients were enrolled and randomly assigned to two groups: HSS-Group (N = 75), in which propofol was administered using a closed-loop system; Control Group (N = 75), in which propofol was delivered manually. The clinical performance of the propofol sedation control is defined as efficacy to maintain bispectral index (BIS) near 65. The clinical control was called 'Excellent', 'Good', 'Poor' and 'Inadequate' with BIS values within 10 %, from 11 to 20 %, 21 to 30 %, or greater than 30 % of the BIS target of 65, respectively. The controller performance was evaluated using Varvel's parameters. Data are presented as mean ± standard deviation, groups were compared using t test or Chi square test, P |
| Databáze: | OpenAIRE |
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