Safety and Acceptability of the PrePex Device When Used in Routine Male Circumcision Service Delivery During Active Surveillance in Zimbabwe
| Autor: | Karin Hatzold, Christopher A. Samkange, Emmanuel Njeuhmeli, Mufuta Tshimanga, Jo Keatinge, Owen Mugurungi, Efison Dhodho, Getrude Ncube, Sinokuthemba Xaba, Webster Mavhu, Ngonidzashe Madidi, Tonderayi Mangwiro, Frances M. Cowan |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
safety Zimbabwe Adult Male medicine.medical_specialty Adolescent Service delivery framework Pain 03 medical and health sciences Young Adult 0302 clinical medicine acceptability male circumcision Medicine Humans Pharmacology (medical) 030212 general & internal medicine Young adult business.industry Middle Aged Patient Acceptance of Health Care 030112 virology Infectious Diseases Circumcision Male Male circumcision Family medicine Odorants Physical therapy Supplement Article PrePex business |
| Zdroj: | Journal of Acquired Immune Deficiency Syndromes (1999) |
| ISSN: | 1944-7884 1525-4135 |
| Popis: | Background: Male circumcision devices have the potential to accelerate voluntary medical male circumcision roll-out, with PrePex being one promising device. Here, we present findings on safety and acceptability from active surveillance of the implementation of PrePex among 1000 males circumcised in Zimbabwe. Methods: The first 1000 men consecutively circumcised using PrePex during routine service delivery were actively followed up. Outcome measures included PrePex uptake, attendance for postcircumcision visits, and adverse events (AEs). A survey was conducted among 500 consecutive active surveillance clients to assess acceptability and satisfaction with PrePex. Results: A total of 2156 men aged 18 years or older were circumcised across the 6 PrePex active surveillance sites. Of these, 1000 (46.4%) were circumcised using PrePex. Among them, 4 (0.4%) self-removals that required surgery (severe AEs) were observed. Six (0.6%) removals by providers (moderate AEs) did not require surgery. A further 280 (28%) AEs were mild or moderate pain during device removal. There were also 12 (1.2%) moderate AEs unrelated to pain. All AEs resolved without sequelae. There was high adherence to follow-up appointments, with 97.7% of clients attending the scheduled day 7 visit. Acceptability of PrePex was high among survey participants, 93% indicated willingness to recommend the device to peers. Of note, 95.8% of respondents reported experiencing pain when the device was being removed. Additionally, 85.2% reported experiencing odor while wearing the device or during removal. Conclusions: Active surveillance of the first 1000 men circumcised using PrePex suggests that the device is both safe and acceptable when used in routine service delivery. |
| Databáze: | OpenAIRE |
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