Paraneoplastic Neurologic Symptoms in a Pediatric Patient with Hodgkin Lymphoma
| Autor: | Sarah S. Donaldson, Catherine Aftandilian, Susan M. Hiniker, Claire C Baniel |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Epstein-Barr Virus Infections Cancer Research medicine.medical_specialty Paraneoplastic Syndromes Achalasia 03 medical and health sciences 0302 clinical medicine otorhinolaryngologic diseases Humans Medicine Endoscopy Digestive System Child business.industry Disease Management General Medicine medicine.disease Hodgkin Disease Dysphagia Dermatology Pediatric patient 030104 developmental biology Oncology 030220 oncology & carcinogenesis Hodgkin lymphoma Female medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Cancer Investigation. :1-7 |
| ISSN: | 1532-4192 0735-7907 |
| DOI: | 10.1080/07357907.2020.1852412 |
| Popis: | Neurological paraneoplastic syndromes are exceedingly rare, and often difficult to recognize clinically. Paraneoplastic achalasia is a condition characterized by new-onset dysphagia that is unrelated to tumor burden, most often due to the development of auto-immune antibodies targeting esophageal tissue. Due to the rarity of this condition, diagnosis is often delayed, leading to increased time to treatment. Here we report a case of a rare paraneoplastic achalasia in a female child with EBV + Hodgkin lymphoma (HL), review literature describing paraneoplastic achalasia, and discuss treatment strategies for improving clinical outcome in these patients. |
| Databáze: | OpenAIRE |
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