Neuro-Ophthalmic Complications of Vestibular Schwannoma Resection: Current Perspectives
| Autor: | Stephanie J Chiu, John Yianni, Jennifer Tan, Irene M Pepper, Simon J Hickman, Joanna M Jefferis |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
post-operative complications genetic structures Lagophthalmos Perforation (oil well) Review Nystagmus Schwannoma Corneal ulceration Cellular and Molecular Neuroscience vestibular schwannoma Cornea neurotrophic keratopathy medicine Cerebral venous sinus thrombosis Papilledema business.industry papilledema medicine.disease eye diseases Sensory Systems Surgery Ophthalmology medicine.anatomical_structure facial nerve paralysis sense organs medicine.symptom business nystagmus |
| Zdroj: | Eye and Brain |
| ISSN: | 1179-2744 |
| DOI: | 10.2147/eb.s272326 |
| Popis: | Vestibular schwannomas (VSs), also called acoustic neuromas, are benign intracranial neoplasms of the vestibulocochlear (VIII) cranial nerve. Management options include “wait-and-scan,” stereotactic radiosurgery and surgical resection. Due to the proximity of the VIII nerve to the facial (VII) nerve in the cerebello-pontine angle, the VII nerve is particularly vulnerable to the effects of surgical resection. This can result in poor eye closure, lagophthalmos and resultant corneal exposure post VS resection. Additionally, compression from the tumor or resection can cause trigeminal (V) nerve damage and a desensate cornea. The combination of an exposed and desensate cornea puts the eye at risk of serious ocular complications including persistent epithelial defects, corneal ulceration, corneal vascularization, corneal melting and potential perforation. The abducens (VI) nerve can be affected by a large intracranial VS causing raised intracranial pressure (a false localizing sign) or as a result of damage to the VI nerve at the time of resection. Other types of neurogenic strabismus are rare and typically transient. Contralaterally beating nystagmus as a consequence of vestibular dysfunction is common post-operatively. This generally settles to pre-operative levels as central compensation occurs. Ipsilaterally beating nystagmus post-operatively should prompt investigation for post-operative cerebrovascular complications. Papilledema (and subsequent optic atrophy) can occur as a result of a large VS causing raised intracranial pressure. Where papilledema follows surgical resection of a VS, it can indicate that cerebral venous sinus thrombosis has occurred. Poor visual function following VS resection can result as a combination of all these potential complications and is more likely with larger tumors. |
| Databáze: | OpenAIRE |
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