Anticipating response to predictive genetic testing for Alzheimer's disease: a survey of first-degree relatives
| Autor: | Roberts Js |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty Health Knowledge Attitudes Practice Genetic counseling Genetic Counseling Disease Alzheimer Disease medicine Humans First-degree relatives Situational ethics Predictive testing Psychiatry Genetic testing Aged Aged 80 and over medicine.diagnostic_test business.industry General Medicine Middle Aged Test (assessment) Health education Female Geriatrics and Gerontology business Gerontology Attitude to Health Clinical psychology |
| Zdroj: | The Gerontologist. 40(1) |
| ISSN: | 0016-9013 |
| Popis: | Two hundred and three children and siblings of patients with Alzheimer's disease (AD) (age range: 30-92 years, 75% female) were surveyed regarding potential predictive testing options for the disorder. A mailed questionnaire posed various hypothetical scenarios and assessed the following variables: interest in testing, perceptions of its pros and cons, and psychological and demographic predictors of test intentions. In 5 of 6 scenarios, a majority of participants expressed intentions to pursue testing, with perceived pros outweighing cons. The most important reasons for seeking testing were informing later-life decisions and planning future AD care. Predictors of test intentions were male gender, information-seeking style, higher perceived AD threat, and appraisal of test pros versus cons. Situational factors such as available treatment options and certainty of test information also affected responses. Results suggest a positive view of predictive testing, with its limitations and risks underrated. Study findings may inform AD genetic counseling and health education efforts. |
| Databáze: | OpenAIRE |
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