Additional file 6 of SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution

Autor: Stow, Emily C., Baddoo, Melody, LaRosa, Alexis J., LaCoste, Dawn, Deininger, Prescott, Belancio, Victoria
Rok vydání: 2022
DOI: 10.6084/m9.figshare.20678854.v1
Popis: Additional file 6. Expression patterns of genes involved in limiting L1 expression and integration in mice. Cell types are abbreviated as follows: Spermatocytes (Spcyt), Round Spermatids (RS), Elongating Spermatids (ES), Condensing Spermatids (CS), Sertoli (Ser), Leydig (Ley). A. Mouse 1 gene expression patterns for Phospholipase D Family Member 6 (PLD6) (A1), Heat Shock Protein 90 Alpha Family Class A Member 1 (HSP90AA1) (A2), and Ubiquitin Like with PHD And Ring Finger Domains 1 (UHRF1) (A3). B. Mouse 2 gene expression patterns for PLD6 (B1), HSP90AA1 (B2), and UHRF1 (B3). C. The heat map shows the normalized expression patterns for each cell type and gene in Mouse 1 (top) and Mouse 2 (bottom). The asterisks indicate a significant change in gene expression in the cell type compared to the preceding cell type in the row (P < 0.0001).
Databáze: OpenAIRE