Cross-coupling reactions with esters, aldehydes, and alcohols
| Autor: | Yan-Long Zheng, Stephen G. Newman |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Addition reaction
010405 organic chemistry Chemistry Metals and Alloys General Chemistry 010402 general chemistry 01 natural sciences Chemical reaction Combinatorial chemistry Catalysis Coupling reaction 3. Good health 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Ceramics and Composites Stoichiometry |
| Zdroj: | Chemical communications (Cambridge, England). 57(21) |
| ISSN: | 1364-548X |
| Popis: | Cross-coupling reactions to form biaryls and π bond addition reactions to prepare substituted carbonyls or alcohols represent two of the most frequently performed families of chemical reactions. Recent progress in catalysis has uncovered substantial overlap between these two seemingly distinct topics. In particular, esters, aldehydes, and alcohols have been shown to act as carbon-based coupling partners in a range of Ni- and Pd-catalyzed reactions to prepare amides, ketones, substituted alcohols, alkanes, and more. These reactions provide promising alternatives to commonly used stoichiometric or multi-step reaction sequences. In this feature article, a selection of these transformations will be discussed with an emphasis on the key mechanistic steps that allow these non-traditional substrates to be incorporated into cross-coupling-like catalytic cycles. |
| Databáze: | OpenAIRE |
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