Mammary carcinogenesis in castrated (C3H x RIII) F1 male mice bearing ovarian transplants in the ear for variable periods of time
| Autor: | R. Assa, I. Muranyi-Kovacs, G. Rudali |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Ovary Male mice Mammary Neoplasms Experimental General Medicine Biology medicine.disease_cause medicine.disease Transplantation Mice surgical procedures operative Endocrinology Internal medicine medicine Neoplasm Mammary carcinogenesis Animals Transplantation Homologous Female Castration Latency (engineering) Ear External Carcinogenesis |
| Zdroj: | European journal of cancer. 13(11) |
| ISSN: | 0014-2964 |
| Popis: | Increase in time of presence of an ovarian transplant on castrated male (C 3 H × R III ) F 1 mice resulted in a decrease in latency time and an increase in the frequencies of mammary tumours. A month long presence of an ovarian transplant was required to stimulate mammary carcinogenesis. The presence of an ovarian graft for either 2 months or throughout the life of the animal induced mammary tumours with a similar frequency. A 3 -month graft, however, was necessary to obtain latency times similar to those observed in animals bearing life long grafts. |
| Databáze: | OpenAIRE |
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