Cryptococcal granulomas in an immunocompromised HIV-negative patient
| Autor: | Juhi Taneja, Poonam Sood Loomba, Aradhana Bhargava, Bibhabati Mishra, Vinita Dogra, Archana Thakur |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Microbiology (medical) Pathology medicine.medical_specialty Antifungal Agents lcsh:QR1-502 Disseminated cryptococcosis lcsh:Microbiology Pathology and Forensic Medicine Immunocompromised Host Central Nervous System Fungal Infections Immunity Amphotericin B HIV Seronegativity Biopsy lcsh:Pathology medicine Dermatomycoses Humans granuloma Fluconazole Cerebrospinal Fluid Cryptococcus neoformans Brain Diseases biology medicine.diagnostic_test business.industry Brain Cryptococcosis General Medicine biology.organism_classification medicine.disease Latex fixation test Radiography immunocompromised Treatment Outcome Granuloma Immunology business lcsh:RB1-214 medicine.drug |
| Zdroj: | Indian Journal of Pathology and Microbiology, Vol 51, Iss 4, Pp 553-555 (2008) |
| ISSN: | 0377-4929 |
| Popis: | Disseminated cryptococcosis usually occurs in immunocompromised individuals with defective cell-mediated immunity, most commonly seen with HIV infection. We present a case of disseminated cryptococcosis in an HIV-negative male patient who presented with headache, fever, altered sensorium of short duration and multiple cutaneous lesions. An emergency CT scan of the head showed multiple intracranial and intraventricular granulomas. Routine laboratory investigations were within the normal range. A CSF examination revealed capsulated yeasts on India ink and a culture yielded cryptococcus neoformans. A cryptococcal antigen test by latex agglutination kit was positive. A biopsy revealed multiple capsulated yeasts cells in the cutaneous lesions, which were consistent with cryptococcus neoformans. The patient was successfully treated with Amphotericin B and Fluconazole with regression of cranial and cutaneous lesions. |
| Databáze: | OpenAIRE |
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