Visual associations cued recall A Paradigm for Measuring Episodic Memory Decline in Alzheimer's Disease
| Autor: | Ben Schmand, Jos F. M. de Jonghe, L. Boelaarts, Pauline E.J. Spaan, Rudolf W. H. M. Ponds, Sascha R. A. Meyer |
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| Přispěvatelé: | FMG, Brein en Cognitie (Psychologie, FMG), RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie, Medical Psychology, Amsterdam Movement Sciences, Amsterdam Neuroscience - Neurodegeneration |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Cross-sectional study Memory Episodic Experimental and Cognitive Psychology Disease Audiology Neuropsychological Tests behavioral disciplines and activities Association 03 medical and health sciences 0302 clinical medicine mild cognitive impairment Alzheimer Disease medicine Humans Cognitive decline Association (psychology) Episodic memory Aged Cued recall Aged 80 and over Memory Disorders 030214 geriatrics episodic memory Alzheimer's disease medicine.disease cognitive decline Cognitive test Psychiatry and Mental health monitoring Neuropsychology and Physiological Psychology Cross-Sectional Studies Mental Recall Regression Analysis Female Geriatrics and Gerontology Cues Psychology 030217 neurology & neurosurgery Photic Stimulation Cognitive psychology |
| Zdroj: | Aging, Neuropsychology, and Cognition, 23(5), 566-577. Taylor and Francis Ltd. Aging Neuropsychology and Cognition, 23(5), 566-577. Routledge/Taylor & Francis Group Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, 23(5), 566-577. Taylor and Francis Ltd. |
| ISSN: | 1382-5585 |
| Popis: | Repeated measurements of episodic memory are needed for monitoring amnestic mild cognitive impairment (aMCI) and mild Alzheimer's disease (AD). Most episodic memory tests may pose a challenge to patients, even when they are in the milder stages of the disease. This cross-sectional study compared floor effects of the Visual Association Test (VAT) and the Rey Auditory Verbal Learning Test (RAVLT) in healthy elderly controls and in patients with aMCI or AD (N = 125). A hierarchical multiple regression analysis was used to examine whether linear or quadratic trends best fitted the data of cognitive test performance across global cognitive impairment. Results showed that VAT total scores decreased linearly across the range of global cognitive impairment, whereas RAVLT total scores showed a quadratic trend, with total scores levelling off for 90% of aMCI patients and 94% of AD patients. We conclude that the VAT shows few if any floor effects in patients with aMCI and mild AD and is therefore a potentially promising cognitive test for monitoring episodic memory impairment. |
| Databáze: | OpenAIRE |
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