Regional variation in lateral and medial gastrocnemius muscle fibre lengths obtained from diffusion tensor imaging
| Autor: | Nicole Y. Kelp, Jeroen Aeles, François Hug, Bart Bolsterlee, Taylor J. M. Dick |
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| Přispěvatelé: | Movement and Sport Sciences |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Male
Histology Intraclass correlation Muscle Fibers Skeletal Medial gastrocnemius Biology Age groups medicine Animals Muscle fibre Muscle Skeletal Molecular Biology Ecology Evolution Behavior and Systematics medicine.diagnostic_test Reproducibility of Results Magnetic resonance imaging Cell Biology Anatomy Magnetic Resonance Imaging Diffusion Tensor Imaging Female Muscle architecture Developmental Biology Diffusion MRI Lateral gastrocnemius |
| Popis: | Assessment of regional muscle architecture is primarily done through the study of animals, human cadavers, or using b-mode ultrasound imaging. However, there remain several limitations to how well such measurements represent in vivo human whole muscle architecture. In this study, we developed an approach using diffusion tensor imaging and magnetic resonance imaging to quantify muscle fibre lengths in different muscle regions along a muscle's length and width. We first tested the between-day reliability of regional measurements of fibre lengths in the medial (MG) and lateral gastrocnemius (LG) and found good reliability for these measurements (intraclass correlation coefficient [ICC] = 0.79 and ICC = 0.84, respectively). We then applied this approach to a group of 32 participants including males (n = 18), females (n = 14), young (24 ± 4 years) and older (70 ± 2 years) adults. We assessed the differences in regional muscle fibre lengths between different muscle regions and between individuals. Additionally, we compared regional muscle fibre lengths between sexes, age groups, and muscles. We found substantial variability in fibre lengths between different regions within the same muscle and between the MG and the LG across individuals. At the group level, we found no difference in mean muscle fibre length between males and females, nor between young and older adults, or between the MG and the LG. The high variability in muscle fibre lengths between different regions within the same muscle, possibly expands the functional versatility of the muscle for different task requirements. The high variability between individuals supports the use of subject-specific measurements of muscle fibre lengths when evaluating muscle function. |
| Databáze: | OpenAIRE |
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