Bone reconstruction after surgical treatment of experimental peri-implantitis defects at a sandblasted/acid-etched hydroxyapatite-coated implant: an experimental study in the dog
| Autor: | Yang-Jo Seol, Yong-Moo Lee, Ulf M.E. Wikesjö, Cristiano Susin, Myung duck Kim, Ki-Tae Koo, Hee Namgoong, In Chul Rhyu, Young Ku, Hee jin Gu |
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| Rok vydání: | 2015 |
| Předmět: |
Dental Implants
Titanium Peri-implantitis Reconstructive surgery medicine.medical_specialty business.industry Surface Properties Dentistry Soft tissue Mandible Beagle Peri-Implantitis Osseointegration Dogs Durapatite medicine Periodontics Animals Implant business Wound healing Bone regeneration Periodontitis |
| Zdroj: | Journal of clinical periodontology. 42(10) |
| ISSN: | 1600-051X |
| Popis: | Objectives The objective of this study was to evaluate bone formation/osseointegration following surgical treatment of experimental peri-implantitis at dental implants with different surface characteristics exposed to ligature-induced breakdown conditions. Methods Ten turned (control), 10 sandblasted/acid-etched (SA), and 10 SA/hydroxyapatite nanocoated (HA) implants were installed into the edentulated posterior mandible in five Beagle dogs and allowed to osseointegrate for 12 weeks. Ligature-induced breakdown defects were then induced over 23 weeks using stainless steel wire ligatures. The ligatures were removed and soft tissues were allowed to heal for 3 weeks. Next, exposed implant surfaces were decontaminated followed by guided bone regeneration using a collagen membrane and submerged wound healing. The animals were euthanized for histometric analysis at 12 weeks post-surgery. Results The radiographic analysis showed vertical bone loss following ligature-induced breakdown without statistically significant differences among implant technologies. The histometric analysis showed significantly enhanced bone formation (height) at SA and SA/HA compared with turned implants (p = 0.028) following reconstructive surgery. Bone formation area was greater at SA/HA compared with turned implants, however the difference did not reach statistical significance. Conclusions While ligature-induced defect progression does not appear implant surface dependent in this animal model, bone formation at the decontaminated implant surfaces appears more favourable at SA and SA/HA over turned implants following reconstructive surgery. |
| Databáze: | OpenAIRE |
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