Comparison of setup accuracy of three different image assessment methods for tangential breast radiotherapy
| Autor: | Penny Phan, Geoff P. Delaney, Vikneswary Batumalai, Callie Choong, Lois Holloway |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Standard of care medicine.medical_treatment Breast Neoplasms Computed tomography Breast radiotherapy Radiotherapy Setup Errors 030218 nuclear medicine & medical imaging 03 medical and health sciences Breast cancer 0302 clinical medicine stomatognathic system Image Interpretation Computer-Assisted Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging In patient electronic portal image (EPI) radiotherapy Aged Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Original Articles cone‐beam computed tomography (CBCT) Cone-Beam Computed Tomography Middle Aged respiratory system equipment and supplies medicine.disease Radiation therapy 030220 oncology & carcinogenesis Digitally reconstructed radiographs Assessment methods Original Article Female Radiology business Nuclear medicine setup errors |
| Zdroj: | Journal of Medical Radiation Sciences |
| ISSN: | 2051-3909 2051-3895 |
| Popis: | Introduction To compare the differences in setup errors measured with electronic portal image (EPI) and cone-beam computed tomography (CBCT) in patients undergoing tangential breast radiotherapy (RT). Relationship between setup errors, body mass index (BMI) and breast size was assessed. Methods Twenty-five patients undergoing postoperative RT to the breast were consented for this study. Weekly CBCT scans were acquired and retrospectively registered to the planning CT in three dimensions, first using bony anatomy for bony registration (CBCT-B) and again using breast tissue outline for soft tissue registration (CBCT-S). Digitally reconstructed radiographs (DRR) generated from CBCT to simulate EPI were compared to the planning DRR using bony anatomy in the V (parallel to the cranio-caudal axis) and U (perpendicular to V) planes. The systematic (Σ) and random (σ) errors were calculated and correlated with BMI and breast size. Results The systematic and random errors for EPI (ΣV = 3.7 mm, ΣU = 2.8 mm and σV = 2.9 mm, σU = 2.5) and CBCT-B (ΣV = 3.5 mm, ΣU = 3.4 mm and σV = 2.8 mm, σU = 2.8) were of similar magnitude in the V and U planes. Similarly, the differences in setup errors for CBCT-B and CBCT-S in three dimensions were less than 1 mm. Only CBCT-S setup error correlated with BMI and breast size. Conclusions CBCT and EPI show insignificant variation in their ability to detect setup error. These findings suggest no significant differences that would make one modality considered superior over the other and EPI should remain the standard of care for most patients. However, there is a correlation with breast size, BMI and setup error as detected by CBCT-S, justifying the use of CBCT-S for larger patients. |
| Databáze: | OpenAIRE |
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