Hair Dye Related Acute Kidney Injury – A Clinical and Experimental Study

Autor:	Y Manjusha, Parvathina Sri Ram Naveen, Chippada Apparao, Yanala Sandeep Reddy, Shaik Abbdul Nabi, Vishnubotla Siva Kumar, Chennu Krishna Kishore, Chinthamaneni Srilatha, Anappindi Sridhar
Rok vydání:	2012
Předmět:	Adult Male medicine.medical_specialty medicine.medical_treatment Hair Dyes Urology Poison control Phenylenediamines Kidney urologic and male genital diseases Critical Care and Intensive Care Medicine Young Adult Hair dyes medicine Animals Humans Young adult Acute tubular necrosis Dialysis urogenital system business.industry Acute kidney injury General Medicine Acute Kidney Injury Middle Aged medicine.disease humanities female genital diseases and pregnancy complications Rats Surgery Nephrology Mesangial proliferative glomerulonephritis Female Hemodialysis business
Zdroj:	Renal Failure. 34:880-884
ISSN:	1525-6049 0886-022X
DOI:	10.3109/0886022x.2012.687346
Popis:	We studied paraphenylenediamine (PPD)-related acute kidney injury (AKI) in 81 patients and also in albino rats experimentally. In the patients' group AKI was found in 32.7%. Of them, 81.4% needed dialysis support. The overall mortality was 25.9%. In experimental rats the renal lesions were noted in all and they were glomerular congestion, intertubular (interstitial) hemorrhages, acute tubular necrosis, mesangial proliferation, and intratubular casts. The severity of renal injury appears to be dose dependent.
Databáze:	OpenAIRE
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